Cains brewery will sell half a million extra pints a year after signing a major deal with a high street pub giant.
The Liverpool brewer will supply 35 Merseyside-based outlets in the Mitchells and Butlers (M&B) estate.
The move is part of a wider strategy from M&B to put regional ales into as many of its 2,000 UK outlets as possible.
Sudarghara Dusanj, joint managing director of Cains, said: "For M&B to take Cains beers throughout its regional venues is a major endorsement of our quality, distribution and availability. The company is renowned for owning some of the best, most profitable and attractive public houses in the North West."
The news means that production at Cains is at its highest level for five years after a string of contract wins for the keg, cask, bottled and canned beers produced at the Liverpool brewery.
M&B has signed up 97 real ales to its regional initiative and each one is going into pubs according to their region.
Adam Martin, marketing director for M&B, said: "We are just going to put the beers on the bar and see how they go. Some will fly and some won't. We hope to grow this campaign. I really hope in a year's time that we are stocking 140 regional beers across the country. That number could fall to 40 - but my hunch is that it will be nearer 100."