The company will be able to trade 24 hours a day at the site at Extra’s Motorway Service Area (MSA) on the M40 (junction 2) at Beaconsfield in Buckinghamshire. It will be allowed to serve alcohol from 8am to 1am seven days a week.
Wetherspoon and Extra are jointly set to invest more than £2m on the development, creating 50 jobs. JDW said no representations against the licence application were received by the council.
Chairman Tim Martin said: "We are looking forward to opening our first licensed bar and restaurant on the motorway network. The company has always been innovative and this is an exciting new development for us.
"Hopefully it will be the first of many Wetherspoon’s on the motorway."
Andrew Long, CEO of Extra MSA Group, said: "Extra continues to invest in further improvements to its chain of MSAs and is committed to providing increased choice and competition for all customers on the motorway network.
"We are pleased to be working closely with JD Wetherspoon as an important new edition to Extra’s substantial complementary range of major and popular tenant partner brands."