Licensee Pauline Forster recently won the right to appeal a High Court decision, which allowed developers to turn a disused nightclub next door to the pub into flats. Forster has long argued that the development will prevent the pub from holding live music events, its "bread and butter", and force it to close earlier.
The charity described the George Tavern as "a test case" for pubs, clubs and other venues facing similar situations around the UK, and said the Court of Appeal will have to consider whether planning authorities should allow new developments if they threaten existing venues or put licences at risk.
Almost 1,000 people have signed the petition so far. Signee Dan Horrigan wrote: "It is entirely sensible that new buildings that are being constructed beside established venues like the George can be built to deal with noise. It should be a requirement of the contractors and the builders to create property with noise-reduction measures."
Forster added: "We desperately need a common-sense approach to planning and music venues and hope that a successful outcome for us can lead the way for other pubs and venues who are having to deal with inappropriate property development."