The Nag’s Head in Haughton, Tarporley is the company’s fifth pub with ongoing negotiations for a second in the county.
Following an extensive refurbishment the pub will open in early June with planning permission already sought and being processed.
"Ribble Valley Inns is a multi-award winning concept with the ethos of using local artisan suppliers to provide the finest food and drink ensuring we deliver a premium pub experience," said chief executive Wayne Chapman.
"Expanding into Cheshire is part of our growth strategy and enabling more customers in different geographic areas to experience the Ribble Valley proposition.
"The refurbishment and refinement process of our existing properties has been extremely successful in encouraging this growth into Cheshire. Cheshire already has some fantastic dining pubs and we’re excited to be competing in such a buoyant market and finding great new Cheshire suppliers to work with."
Existing sites the Three Fishes in Whalley and the Clog and Billycock in Pleasington, both in Lancashire, have already been refurbished.