The new bar, in Dundee, is the fifth to be opened by the company this year, following launches in Gothenburg, São Paulo, Tokyo and Sheffield.
BrewDog now operates 18 sites globally, and is promising further international expansion in the coming months with new bars planned for Clapham, Brighton, Rome and Florence.
The newest bar, which can hold 80 people, is located on the ground floor of Dundee’s historic Chambers Building, previously the city’s Stock Exchange.
BrewDog plans to host 18 beers on tap and showcase the brewery’s own range of beers alongside guest beers from international craft breweries.
Guest craft beers include Weihenstephan, Magic Rock Brewing, Clown Shoes, Mikkeller, Anchor, and Williams Brothers.
The bar will serve gourmet sandwiches, meat and cheese platters and BrewDog beer-infused cakes, baked by local bakery Jessie’s Kitchen.
BrewDog co-founder James Watt said: “Dundee is a hugely exciting city, rich with Scottish history and culture, and home to thousands of passionate beer drinkers.
“Craft beer fans in the city have been crying out for a BrewDog bar for years and we’re thrilled to finally set up a BrewDog home there.”
In April, BrewDog opened its first off-licence, BottleDog, in London’s Kings Cross area and plans to open a series of the shops over the next 12 months.
The brewery raised £4.25m last year during the third round of its crowdfunding scheme Equity for Punks. It also opened a new brewery in Ellon, Aberdeenshire, which boosted production capacity from 25,000 hectolitres to 250,000 hectolitres per year.