The NFL is back in Britain, transforming London’s famous Twickenham rugby ground into a football arena where the Arizona Cardinals and Los Angeles Rams will battle it out.
Sky Sports Action will be broadcasting the match live this Sunday - coverage runs from 5.15pm until 9pm, with the kick-off at 6pm. More than 80,000 fans piled into Wembley for the Ravens and Jags game earlier this year, as the appetite for American sports in the UK rises.
But before the oval ball starts to get thrown around at Wembley, there are two vital round-ball clashes in the Premier League - first up Everton and Arsenal go head-to-head at Goodison Park, while a little later Tottenham play host to Liverpool.
Everton won two of their last four Premier League home matches against Arsenal, having failed to win any of the previous six against them. More importantly, however, on current form, Everton, and manager Ronald Koeman in particular, have a lot to prove, having failed to register a win in their last four games in all competitions.
Spent £100m on players
And in the Premier League, having spent £100m on players last season, they sit just two points above the relegation zone having registered just two wins from eight league games.
Fun fact: it is 15 years since Everton striker Wayne Rooney scored his first Premier League goal against Arsenal in October 2002 - and he has since scored more goals against the Gunners than any other player in the League.
The second match of the Premier League double-header pits Tottenham Hotspur against Liverpool. On current form Tottenham will have high hopes they can turn the tables against Liverpool after walking away from their last nine encounters without a win. Spurs currently sit third in the table with five wins and 17 points under their belt, while Liverpool are eighth with three wins and 13 points.
Both matches will be screened on Sky Sports Premier League. Coverage of the Everton v Arsenal match runs from 12.30pm to 3.30pm with the kick-off at 1.30pm, while coverage of the Spurs v Liverpool clash runs from 3.30pm to 7pm with the kick-off at 4pm.
This weekend isn’t all about ball games, though, and features plenty of variety, from unification boxing matches to Formula One.
- Boxing: Ryan Burnett V Zhanat Zhakiyanov (Saturday, 21 October, 7.30pm–11.30pm) – Sky Sports Action
This is a massive unification fight for the IBF and WBA Super world bantamweight titles at the SSE Arena in Belfast. Both fighters will be defending unbeaten records.
- Tennis: ATP World Tour Kremlin Cup (Saturday, 21 October, 11am-1.30pm) and WTA Finals, Singapore (Sunday, 22 October, 9.30am-2.45pm) – BT Sport 2
- Formula One: US Grand Prix Qualifying (Saturday, 21 October, 9pm-11.40pm) and US Grand Prix Race (Sunday, 22 October, 6.30pm-11.15pm) – Sky Sports F1
- Rugby: Wasps v Harlequins (Sunday, 22 October, 5pm-7.30pm), BT Sport 2
Sky Sports has announced the following 17 live games that will be shown exclusively live throughout December, meaning pubs and clubs can show a total of 34 Premier League games between now and 28 December.
Chelsea v Newcastle Utd
Bournemouth v Southampton
Man City v West Ham Utd
West Ham Utd v Chelsea
Liverpool v Everton
Man Utd v Man City
Leicester City v Crystal Palace
WBA v Man Utd
Bournemouth v Liverpool
Everton v Swansea
Arsenal v Liverpool
Everton v Chelsea
Leicester City v Man Utd
Spurs v Southampton
Liverpool v Swansea City
Newcastle Utd v Man City
Crystal Palace v Arsenal
*NB: Subject to EFL Cup, but will remain a Sky live game