Dickie, who founded the Scottish brewer and pub company with James Watt in 2007, recently launched a medical cannabis business.
Earlier this year, he said he aims to be one of the UK’s top legal farms for medical cannabis, with plans to invest £20m into Waterside Pharmaceuticals over the next five years.
Dickie’s decision will not result in changes to the company’s leadership team.
In an email to BrewDog staff on 22 August, Dickie wrote: “This business has been my life for the last 18 years and I have enjoyed (almost) every minute.
“I have been inspired by and loved working with and learning from so many interesting people who have worked in our business over the years from all over the world.”
He concluded: “People are spending their hard-earned money on something we have made … Make their BrewDog moment special.
“I’m excited to watch from the sidelines as your biggest supporter as you continue to push the business forward with your talent and drive.”
BrewDog CEO James Taylor said Dickie has made an “immeasurable” contribution to the company, adding, “His creativity, passion, and relentless drive have shaped our company over the years and inspired countless others in the industry.”
Last year, co-founder James Watt stepped down from his role as CEO, moving into the position of ‘captain and co-founder’.
Dickie’s decision comes after BrewDog announced plans to rationalise its estate earlier this summer. The company will close 10 bars, including its flagship pub in Aberdeen, citing rising costs and a challenging macroeconomic backdrop.